Document 0052
 DOCN  M9460052
 TI    Werner's syndrome associated with spastic paraparesis and peripheral
       neuropathy.
 DT    9408
 AU    Umehara F; Abe M; Nakagawa M; Izumo S; Arimura K; Matsumuro K; Osame M;
       Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima
       University, Japan.
 SO    Neurology. 1993 Jun;43(6):1252-4. Unique Identifier : AIDSLINE
       MED/94224363
 AB    A Werner's syndrome patient with spastic paraparesis and polyneuropathy
       had slowing of central and peripheral nerve conduction. Sural nerve
       biopsy revealed a significantly higher frequency of demyelination and
       remyelination and a loss of myelinated fibers. These data suggest that
       the central and peripheral nervous systems are affected in Werner's
       syndrome.
 DE    Adult  Case Report  Demyelinating Diseases/*ETIOLOGY  Female  Human
       Paraparesis, Tropical Spastic/*ETIOLOGY  Peripheral Nervous System
       Diseases/*ETIOLOGY  Sural Nerve/PATHOLOGY  Werner's Syndrome/*DIAGNOSIS
       JOURNAL ARTICLE

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