Document 0053 DOCN M9460053 TI Human immunodeficiency virus-related headache. DT 9408 AU Brew BJ; Miller J; Centre for Immunology, St. Vincent's Hospital, Sydney, Australia. SO Neurology. 1993 Jun;43(6):1098-100. Unique Identifier : AIDSLINE MED/94224330 AB We retrospectively assessed the frequency and clinical characteristics of headache occurring in human immunodeficiency virus (HIV)-infected patients in whom we had excluded all other causes, and determined the frequency of a similar headache in an HIV-negative group. Over a 1-year period, the HIV-related headache occurred in 2.8% of total admissions to the HIV service as opposed to 0.2% of admissions to the neurology service. The affected patients had advanced HIV infection (CD4+ cell count = 58.9 +/- 80.3; normal, > 500 x 10(-6)/l). The headache had features similar to those ascribed to HIV aseptic meningitis and was not related to the presence of AIDS dementia complex or its subsequent development over a 6-month follow-up. We propose that this is a distinct clinical entity related to HIV infection that is similar, if not identical, to HIV aseptic meningitis except for the lack of a CSF pleocytosis, probably reflecting the lymphocyte depletion that is characteristic of the more advanced state of HIV infection. DE AIDS Dementia Complex/COMPLICATIONS Follow-Up Studies Headache/*ETIOLOGY Human HIV Infections/*COMPLICATIONS Retrospective Studies JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).