Document 0109
 DOCN  M9460109
 TI    Repeated bereavement, depressed mood, and immune parameters in HIV
       seropositive and seronegative gay men.
 DT    9408
 AU    Kemeny ME; Weiner H; Taylor SE; Schneider S; Visscher B; Fahey JL;
       Department of Psychiatry and Biobehavioral Sciences, School of;
       Medicine, University of California, Los Angeles 90024.
 SO    Health Psychol. 1994 Jan;13(1):14-24. Unique Identifier : AIDSLINE
       MED/94222012
 AB    The relationships among bereavement, depressed mood, and immunologic
       patterns prognostic for the development of acquired immunodeficiency
       syndrome (AIDS) were determined in a sample of human immunodeficiency
       virus (HIV) seropositive gay men and a comparison group of HIV
       seronegative gay men. Immunologic parameters were assessed in 45 men who
       had recently experienced the deaths of close friends and 45 matched
       nonbereaved men. No immune differences were found between bereaved and
       nonbereaved men. Among the HIV seropositive nonbereaved men, higher
       depressed mood was significantly associated with fewer CD4
       (helper/inducer) T lymphocytes, more activated CD8
       (suppressor/cytotoxic) T cells, and lower proliferative responses to the
       mitogen phytohemagglutinin. In summary, HIV seropositive men who
       reported higher levels of depressed mood not associated with bereavement
       demonstrated immunologic patterns consistent with HIV activity and
       progression.
 DE    Acquired Immunodeficiency Syndrome  Adolescence  Adult  Antibodies,
       Monoclonal/IMMUNOLOGY  *Bereavement  Cohort Studies  Depressive
       Disorder/DIAGNOSIS/*IMMUNOLOGY/*PSYCHOLOGY  *Homosexuality  Human  HIV
       Seropositivity/DIAGNOSIS/*IMMUNOLOGY  Lymphocytes/IMMUNOLOGY  Male
       Middle Age  Questionnaires  Sex Behavior  Support, Non-U.S. Gov't
       Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).