Document 0171
 DOCN  M9460171
 TI    Lichenoid photoeruptions in human immunodeficiency virus infection.
 DT    9408
 AU    Berger TG; Dhar A; Department of Dermatology, University of California,
       San; Francisco.
 SO    Arch Dermatol. 1994 May;130(5):609-13. Unique Identifier : AIDSLINE
       MED/94234739
 AB    BACKGROUND: The clinical features of lichenoid eruptions in the setting
       of human immunodeficiency virus (HIV) infection are poorly described.
       Idiopathic lichen planus is rarely reported. All patients (n = 32) with
       a histologic diagnosis of a lichenoid eruption or photodermatitis at the
       University of California, San Francisco, over a 15-month period were
       reviewed and studied. OBSERVATIONS: Twelve of the 32 patients were HIV
       infected, and all 12 had photodistributed eruptions. Ten of 12 patients
       had received photosensitizing medication (usually nonsteroidal
       anti-inflammatory drugs or sulfamethoxazole/trimethoprim) at the onset
       of eruption. Most patients were black (10 of 12), and all had acquired
       immunodeficiency syndrome and a helper T-cell count of less than 50
       cells per cubic milliliter. Nine patients had lichenoid eruptions, two
       showed histopathologic features of lichen niditus, and one had a
       photodistributed subacute dermatitis. Two patients with lichenoid
       eruptions developed marked depigmentation. No cases of lichen planus
       were found in HIV-infected persons. CONCLUSION: Lichenoid photoeruptions
       are seen in advanced HIV disease (CD4, < 0.05 x 10(9)L), and black
       patients are disproportionately affected. Idiopathic lichen planus in
       HIV-infected patients seems to be less common than lichenoid
       photoeruptions. Previously reported cases of idiopathic lichen planus in
       HIV-infected patients may represent lichenoid photodermatitis.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  Aged  Female
       Human  Lichenoid Eruptions/*COMPLICATIONS/PATHOLOGY  Male  Middle Age
       Photosensitivity Disorders/*COMPLICATIONS/PATHOLOGY  JOURNAL ARTICLE

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