Document 0753
 DOCN  M9470753
 TI    Helicobacter cinaedi-associated bacteremia and cellulitis in
       immunocompromised patients.
 DT    9409
 AU    Kiehlbauch JA; Tauxe RV; Baker CN; Wachsmuth IK; Centers for Disease
       Control and Prevention, Atlanta, Georgia.
 SO    Ann Intern Med. 1994 Jul 15;121(2):90-3. Unique Identifier : AIDSLINE
       MED/94288394
 AB    OBJECTIVE: To define the clinical spectrum of illness associated with
       Helicobacter cinaedi infection in the United States and to determine
       associated epidemiologic risk factors and optimal laboratory methods for
       recovery of H. cinaedi. DESIGN: A retrospective epidemiologic study of
       23 patients with H. cinaedi-associated illness. PATIENTS: 23 patients
       with H. cinaedi infection identified between January 1982 and August
       1990. Most isolates (22 of 23) were from blood; one was from stool.
       RESULTS: Ages ranged from 24 to 84 years (mean, 44 years). Eighty-three
       percent of patients were men; 17% were women. Clinical and laboratory
       data were obtained from 21 patients. Eighteen patients were febrile (15
       required hospitalization); cellulitis was reported in 9 patients. Sixty
       percent were immunocompromised; 45% were reported to be seropositive for
       human immunodeficiency virus (HIV). For bacteremic patients, positive
       blood cultures were detected by a slightly elevated growth index in an
       automated blood culture system; many hospital laboratories had
       difficulty isolating the organism. CONCLUSIONS: Helicobacter cinaedi
       appears to cause recurrent cellulitis with fever and bacteremia in
       immunocompromised hosts. Blood cultures from immunocompromised patients
       with these symptoms may need special handling to isolate H. cinaedi.
 DE    Adult  Aged  Aged, 80 and over  Bacteremia/DRUG
       THERAPY/*EPIDEMIOLOGY/MICROBIOLOGY  Case Report  Cellulitis/DRUG
       THERAPY/*EPIDEMIOLOGY/MICROBIOLOGY  Female  Helicobacter/*ISOLATION &
       PURIF  Helicobacter Infections/DRUG THERAPY/*EPIDEMIOLOGY/MICROBIOLOGY
       Human  HIV Seropositivity  *Immunocompromised Host  Male  Microbial
       Sensitivity Tests  Middle Age  Retrospective Studies  Risk Factors
       Support, U.S. Gov't, P.H.S.  United States/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).