Document 0778
 DOCN  M9470778
 TI    [HIV infection in children]
 DT    9409
 AU    Christiansen CB; Heilmann CJ; Statens Seruminstitut, virologisk
       afdeling, Kobenhavn.
 SO    Ugeskr Laeger. 1994 Apr 25;156(17):2568-70, 2573-5. Unique Identifier :
       AIDSLINE MED/94287558
 AB    More children will be born infected with HIV in the years to come.
       Children with early symptoms will come into quick contact with a
       hospital, while others may be infected for up to ten years without
       presenting HIV-related symptoms. HIV infection can be diagnosed early
       with a combination of methods that are currently available (viral
       culture, ELISA antigen testing), and also with methods that are at
       present only used in research (DNA and RNA detection with PCR). Together
       with the clinical picture, it should be possible to have a reliable
       diagnosis no later than six months after birth. The general development
       of the children can be followed at frequent out-patient visits, while
       prophylactic measures can quickly be put into motion when necessary. The
       course of the illness can be followed and predicted with the help of
       different laboratory investigations. The medical treatment of HIV
       positive children follows the pattern of adult HIV positive patients.
       Children with an increased risk of bacterial infections can receive
       intravenous immune globulin as prophylaxis. HIV infected children can be
       given the common vaccinations, but BCG and oral anti-polio vaccine
       should not be given to children with symptomatic HIV infection.
       Prophylaxis of vertical transmission of HIV should be aimed at HIV
       testing of all pregnant women, to prevent this route of transmission. As
       long as there is no efficient treatment of HIV infection, termination of
       pregnancy must be recommended early after conception to all HIV positive
       women. Children born of HIV positive mothers should not be breast-fed.
 DE    Acquired Immunodeficiency Syndrome/*DIAGNOSIS/PREVENTION &
       CONTROL/TRANSMISSION  Denmark/EPIDEMIOLOGY  English Abstract  Female
       Human  HIV Seropositivity/*DIAGNOSIS  Infant, Newborn  Pregnancy
       Pregnancy Complications, Infectious/PREVENTION & CONTROL  Prognosis
       JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).