Document 0789 DOCN M9470789 TI Case report 836: Malignant large cell lymphoma of sacrum. DT 9409 AU Ackerman L; Van Drunen M; Reyes CV; Nuclear Medicine Service, Edward Jr. Hines Veterans; Administration Hospital, Hines, Illinois. SO Skeletal Radiol. 1994 Apr;23(3):232-5. Unique Identifier : AIDSLINE MED/94287227 AB We present a case of PLB found in the sacrum in an HIV-seropositive patient who had low back pain radiating to the lower extremities. To the best of our knowledge this is the first report of this kind. Multiple imaging techniques, including MRI, could not reliably differentiate between neoplasm and infection. Both processes were considered since the patient was not only HIV-seropositive but also was an intravenous drug abuser and had a history of TB. The biopsy revealed diffuse large cell lymphoma typical of AIDS patients. The unusual location of PLB in our patient is a characteristic feature of lymphoma in patients with AIDS and our case should increase awareness among clinicians and radiologists of this possibility. DE Adult Biopsy, Needle Case Report Diagnosis, Differential Diagnostic Imaging Human *HIV Seropositivity Lymphoma, AIDS-Related/*PATHOLOGY Lymphoma, Large-Cell, Diffuse/*PATHOLOGY Male Sacrum/*PATHOLOGY Spinal Neoplasms/*PATHOLOGY JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).