Document 0817
 DOCN  M9470817
 TI    [Surgical treatment of anorectal disorders in 32 HIV-seropositive
       patients]
 DT    9409
 AU    Sars PR; Slors JF; Taat CW; Academisch Medisch Centrum, afd. Chirurgie,
       Amsterdam.
 SO    Ned Tijdschr Geneeskd. 1994 Jun 11;138(24):1227-30. Unique Identifier :
       AIDSLINE MED/94286024
 AB    OBJECTIVE. To describe the presentation and surgical treatment of
       anorectal pathology in HIV seropositive patients. DESIGN. Retrospective
       study. SETTING. Department of surgery, University Medical Centre,
       Amsterdam, the Netherlands. METHODS. Retrospective review of the records
       of 32 HIV seropositive patients surgically treated for anorectal
       pathology in 1985-1992. RESULTS. The 32 patients, homosexual males, had
       a total of 46 diagnoses for which they underwent 49 surgical
       interventions. Sixteen patients had an anorectal ulcer (14 in the anal
       canal, 2 in the distal rectum); 7 were treated by local excision and 9
       with additional advancement of the anal mucosa; there were 4 and 2
       recurrences, respectively. Ten patients had a perianal abscess; 5 a
       fistula, 2 of whom initially presented with a metastatic abscess in
       liver and brain. Eight patients had perianal warts, which in 2 cases
       showed severe dysplasia and in one an infiltrating carcinoma. Five
       patients presented primarily with a malignancy (3 with squamous cell
       carcinoma of the anus, 1 with cloacogenic carcinoma, 1 with non-Hodgkin
       lymphoma distally in the rectum). Twelve patients died within 6 months
       after the first operation. CONCLUSION. In choosing therapy for anorectal
       disorders, the limited survival of HIV seropositive patients, especially
       those with an advanced stage of AIDS should be considered. Surgical
       treatment can improve the quality of life in these patients.
 DE    Adult  Anus Diseases/COMPLICATIONS/*SURGERY  English Abstract
       Homosexuality  Human  *HIV Seropositivity  Life Expectancy  Male  Middle
       Age  Quality of Life  Rectal Diseases/COMPLICATIONS/*SURGERY
       Retrospective Studies  JOURNAL ARTICLE

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