Document 0869
 DOCN  M9470869
 TI    Laparoscopic and histologic findings in patients with the human
       immunodeficiency virus.
 DT    9409
 AU    Jeffers LJ; Alzate I; Aguilar H; Reddy KR; Idrovo V; Cheinquer H; Hasan
       FA; Parker T; Montero C; Dickinson G; et al; Division of Hepatology,
       University of Miami School of Medicine,; Florida.
 SO    Gastrointest Endosc. 1994 Mar-Apr;40(2 Pt 1):160-4. Unique Identifier :
       AIDSLINE MED/94283794
 AB    Hepatic dysfunction frequently develops in patients infected with the
       human immunodeficiency virus (HIV). This retrospective study was
       undertaken to determine the laparoscopic and histologic findings in a
       group of HIV-seropositive patients with or without the acquired immune
       deficiency syndrome (AIDS). Fifty-four patients, 44 with AIDS and 10
       HIV-positive, underwent laparoscopic examination and visually guided
       biopsies for the assessment of clinical or biochemical evidence of liver
       injury. Significant abnormalities were detected in 31/44 (70%) AIDS
       patients and 3/10 (30%) HIV-positive patients. Overall, specific
       laparoscopic findings were described in 25/54 (46%). The most common
       findings were peritoneal involvement, massive intra-abdominal adhesions,
       focal lesions of the liver or spleen, and diffuse nodularity of the
       liver; these were usually related to opportunistic infections or
       neoplasms such as non-Hodgkin's lymphomas and Kaposi's sarcoma. No
       procedure-related deaths occurred. Laparoscopy is a safe and accurate
       method to detect underlying disease in a selected population of
       HIV-seropositive patients.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS
       Adhesions/DIAGNOSIS/EPIDEMIOLOGY  Adult  AIDS-Related Opportunistic
       Infections/*DIAGNOSIS/EPIDEMIOLOGY  Biopsy  Female  Human  HIV
       Seropositivity  Laparoscopy  Liver/*PATHOLOGY  Liver
       Diseases/*COMPLICATIONS/*DIAGNOSIS/EPIDEMIOLOGY  Male  Peritoneal
       Diseases/*COMPLICATIONS/*DIAGNOSIS/EPIDEMIOLOGY  Retrospective Studies
       Risk Factors  Splenic Diseases/*COMPLICATIONS/*DIAGNOSIS/EPIDEMIOLOGY
       Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).