Document 0918
 DOCN  M9470918
 TI    Clinical epidemiological study of 171 cases of cryptococcosis.
 DT    9409
 AU    Rozenbaum R; Goncalves AJ; Servico de Doencas Infecciosas e
       Parasitarias, Hospital dos; Servidores do Estado do Rio de Janeiro,
       Brazil.
 SO    Clin Infect Dis. 1994 Mar;18(3):369-80. Unique Identifier : AIDSLINE
       MED/94281417
 AB    We retrospectively studied 171 patients with cryptococcosis who were
       divided into three groups according to their associated predisposing
       conditions (if any): group 1 comprised nonimmunosuppressed patients,
       group 2 comprised patients with AIDS, and group 3 comprised those
       patients with other conditions and/or who were users of
       immunosuppressive drugs. Analysis and correlation of the behavior of the
       mycosis among the three groups showed differences in the demographic
       data, clinical forms and manifestations of cryptococcosis, laboratory
       results, morbidity and mortality rates, and histopathologic aspects.
       Study of the clinical isolates of Cryptococcus neoformans from 83
       patients with cryptococcosis showed that 75 were characterized as C.
       neoformans variety neoformans and eight as C. neoformans var. gatti.
       Comparison of the distribution of the gattii and neoformans varieties
       between the nonimmunosuppressed (group 1) and immunosuppressed (groups 2
       and 3) patients showed a significant statistical difference (P < .01).
 DE    Adolescence  Adult  Aged  Aged, 80 and over  AIDS-Related Opportunistic
       Infections/COMPLICATIONS/EPIDEMIOLOGY  Brazil/EPIDEMIOLOGY  Child
       Child, Preschool  Cryptococcosis/COMPLICATIONS/*EPIDEMIOLOGY/IMMUNOLOGY
       Cryptococcus/CLASSIFICATION/ISOLATION & PURIF  Female
       Fungemia/COMPLICATIONS/EPIDEMIOLOGY  Human  Immune Tolerance  Lung
       Diseases, Fungal/COMPLICATIONS/EPIDEMIOLOGY  Male
       Meningoencephalitis/COMPLICATIONS/EPIDEMIOLOGY  Middle Age
       Retrospective Studies  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).