Document 0956
 DOCN  M9470956
 TI    Modeling the impact and cost-effectiveness of HIV prevention efforts.
 DT    9409
 AU    Rowley JT; Anderson RM; Biology Department, Imperial College of Science,
       Technology and; Medicine, London, UK.
 SO    AIDS. 1994 Apr;8(4):539-48. Unique Identifier : AIDSLINE MED/94280729
 AB    OBJECTIVES: This study explores how mathematical models can be used to
       examine the relationship between the effectiveness and costs of
       different prevention strategies. The analysis, based on a model designed
       to simulate the spread of HIV in sub-Saharan Africa, illustrates how the
       impact and relative cost-effectiveness of a prevention programme are
       sensitive to a number of factors including the rate of spread of HIV
       prior to the introduction of the programme, the measure used to evaluate
       the impact of the programme, and the point when the programme is
       introduced in the epidemic. RESULTS: Assessing the impact and
       cost-effectiveness of different HIV prevention strategies is
       problematic. Not only are there difficulties in collecting the relevant
       data, but the impact of a prevention programme may be highly non-linear
       in character because of the many factors that determine the net rate of
       viral transmission. The long incubation period of HIV further
       complicates the analysis as the benefits from preventing a case of
       infection extend over a number of years. CONCLUSIONS: The results
       highlight the need to collect more data on the impact and costs of
       prevention programmes if we are to ensure that the available resources
       for HIV prevention are to be used both efficiently and equitably.
 DE    Africa South of the Sahara  Cost-Benefit Analysis  Costs and Cost
       Analysis  Female  Human  HIV Infections/*ECONOMICS/*PREVENTION & CONTROL
       Male  Models, Theoretical  Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).