Document 0132 DOCN M9480132 TI Working memory in individuals with HIV infection. DT 9410 AU Law WA; Martin A; Mapou RL; Roller TL; Salazar AM; Temoshok LR; Rundell JR; Henry M. Jackson Foundation for the Advancement of Military; Medicine, Rockville, Maryland. SO J Clin Exp Neuropsychol. 1994 Apr;16(2):173-82. Unique Identifier : AIDSLINE MED/94292566 AB The central executive component (CE) of Baddeley's working memory model (Baddeley, 1992) was evaluated in 26 asymptomatic human immunodeficiency virus-infected individuals (HIV+) and 23 HIV-control subjects using a dual-task working memory paradigm. The HIV+ and HIV- groups showed an equivalent reduction in performance on both the primary task (visual vigilance) and the secondary task (letter span) when they were performed concurrently relative to when either task was performed alone. This result suggested normal CE functioning in these HIV+ subjects. In contrast, the HIV+ subjects had significantly longer response latencies on reaction time measures relative to the HIV- control group. These findings indicated that slowed processing in early stage HIV-infected individuals is not associated with a working memory deficit. DE Adult Attention AIDS Dementia Complex/*DIAGNOSIS/PSYCHOLOGY Female Human HIV Seropositivity/*DIAGNOSIS/PSYCHOLOGY Longitudinal Studies Male Military Personnel/*PSYCHOLOGY *Neuropsychological Tests Pattern Recognition, Visual Psychomotor Performance Reaction Time *Recall Retention (Psychology) Serial Learning Support, U.S. Gov't, Non-P.H.S. Verbal Learning JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).