Document 0143
 DOCN  M9480143
 TI    [The occurrence of immunological tolerance to inhibitors of factors VIII
       and IX in hemophilia patients]
 DT    9410
 AU    Brakman GG
 SO    Gematol Transfuziol. 1993 Feb;38(2):18-20. Unique Identifier : AIDSLINE
       MED/94291906
 AB    To abolish inhibitors, 40 out of 60 hemophiliacs (57 patients and 3 with
       hemophilia A and B, respectively) were treated according to the
       therapeutic scheme specified as Bonn protocol. A complete disappearance
       of the inhibitors was achieved in all the patients. These were followed
       up for 13 years during which they received on demand standard hemostatic
       treatment. No inhibitors have been registered so far.
 DE    Adolescence  Adult  Child  Child, Preschool  Christmas
       Disease/COMPLICATIONS/*IMMUNOLOGY/THERAPY  English Abstract  Factor
       IX/ADMINISTRATION & DOSAGE/*ANTAGONISTS & INHIB/ANALYSIS/  IMMUNOLOGY
       Factor VIII/ADMINISTRATION & DOSAGE/*ANTAGONISTS & INHIB/ANALYSIS/
       IMMUNOLOGY  Hemophilia/COMPLICATIONS/*IMMUNOLOGY/THERAPY  Human  HIV
       Antibodies/BLOOD  HIV Seropositivity/EPIDEMIOLOGY  HIV-1/IMMUNOLOGY
       *Immune Tolerance  Infant  Middle Age  Risk Factors  Time Factors
       JOURNAL ARTICLE

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