Document 0155
 DOCN  M9480155
 TI    Comparison of four commercial enzyme-linked immunosorbent and one
       agglutination assays for the detection of HIV antibodies in sera from
       Zimbabwe.
 DT    9410
 AU    Tswana SA; Moyo SR; Nystrom L; Blomerg J; Department of Medical
       Microbiology, University of Zimbabwe; Medical School, Harare.
 SO    Cent Afr J Med. 1993 Oct;39(10):198-201. Unique Identifier : AIDSLINE
       MED/94291172
 AB    Sera from 871 AIDS and AIDS related complex patients were used to
       evaluate four ELISA and one agglutination assays. Commercial tests
       compared were Abbot, Wellcoyzyme, Biotest, Du Pont and Serodia.
       Wellcozyme and Serodia had the highest sensitivity (96.8 pc and 98.8 pc
       respectively) but the lowest specificity (53.3 pc and 46.5 pc
       respectively). Du Pont was the least sensitive test (89.1pc). Biotest
       and Abbot were comparable--Biotest had a higher sensitivity (93.2pc as
       compared with 90.6pc) but Abbot had a higher specificity (94.1 pc as
       compared with 89.1 pc). Thus, Abbott and Biotest both had a satisfactory
       high sensitivity and specificity and could thereby be recommended for
       use in screening of HIV-1 antibodies in south east Africa.
 DE    Acquired Immunodeficiency Syndrome/*BLOOD/EPIDEMIOLOGY/PREVENTION  &
       CONTROL  Agglutination Tests/*STANDARDS  AIDS-Related
       Complex/*BLOOD/EPIDEMIOLOGY/PREVENTION & CONTROL  Blotting, Western
       Comparative Study  Enzyme-Linked Immunosorbent Assay/*METHODS/*STANDARDS
       Evaluation Studies  Human  HIV Antibodies/*BLOOD  *HIV-1  *HIV-2  Mass
       Screening/METHODS  Sensitivity and Specificity  Support, Non-U.S. Gov't
       Zimbabwe/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).