Document 0512
 DOCN  M9480512
 TI    Improvement in CD4 lymphocyte count in HIV-Reiter's syndrome after
       treatment with sulfasalazine.
 DT    9410
 AU    Disla E; Rhim HR; Reddy A; Taranta A; Department of Medicine, Cabrini
       Medical Center, New York, NY; 10003.
 SO    J Rheumatol. 1994 Apr;21(4):662-4. Unique Identifier : AIDSLINE
       MED/94309030
 AB    OBJECTIVE. To describe an observed improvement in CD4 lymphocytes in
       patients with Reiter's syndrome (RS) and human immunodeficiency virus
       (HIV) infection, after treatment with sulfasalazine (SFSZ). METHODS .
       Care series. We analyzed CD4 lymphocyte counts in 4 consecutive patients
       with RS and HIV disease before and after treatment with SFSZ. RESULTS.
       CD4+ lymphocyte counts increased from a mean of 315 +/- 179 before
       treatment to 542 +/- 231 x 10(6)/l on followup (p < 0.03), in the
       absence of antiretroviral therapy. The significance of these
       observations is discussed. CONCLUSION. Treatment of RS with SFSZ in HIV
       disease appears to be associated with an improvement in CD4 count.
 DE    Adult  Case Report  CD4-CD8 Ratio/DRUG EFFECTS  Human  HIV
       Infections/BLOOD/COMPLICATIONS/*DRUG THERAPY  Leukocyte Count  Male
       Middle Age  Reiter's Disease/BLOOD/COMPLICATIONS/*DRUG THERAPY
       Salicylazosulfapyridine/*THERAPEUTIC USE  Time Factors  T4
       Lymphocytes/*DRUG EFFECTS  JOURNAL ARTICLE

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