Document 0515 DOCN M9480515 TI Human immunodeficiency virus serostatus and the risk of postextraction complications. DT 9410 AU Dodson TB; Perrott DH; Gongloff RK; Kaban LB; Department of Surgery, Emory University, Atlanta, GA. SO Int J Oral Maxillofac Surg. 1994 Apr;23(2):100-3. Unique Identifier : AIDSLINE MED/94308633 AB Despite the increasing prevalence of human immunodeficiency virus (HIV) disease in the population and the increasing likelihood that HIV-positive (HIV+) patients may have an extraction, little is known about the risk of postoperative complications in this group. The goal of this investigation was to assess the risk of postoperative complications in HIV+ patients after tooth extraction. The study was designed as a retrospective cohort study with a sample consisting of 145 males who underwent tooth extraction. The patients' medical and dental records were reviewed to identify HIV serostatus, to document the frequency and type of postoperative complications, and to collect data on potential confounding variables. Forty-four patients were identified as HIV+. The postoperative complication rate in HIV+ patients was 20.9% and for HIV-negative (HIV-) patients 2.9% (relative risk = 7.0, 95% confidence interval = 2.0-25.0, P = 0.001). Furthermore, as the manifestations of the symptoms of HIV infection became more severe, the postextraction complication rate also increased (P = 0.008). The results of this study suggest that HIV+ patients have an increased risk of postextraction complications and as the level of HIV disease increases, the risk of complications also increases. While the findings of this study are consistent with studies based on case series, prospective cohort studies are required to confirm the findings. DE Acquired Immunodeficiency Syndrome Adult Age Factors Alcohol Drinking Analysis of Variance Antibiotics/THERAPEUTIC USE AIDS-Related Complex Chi-Square Distribution Cohort Studies Comparative Study Confounding Factors (Epidemiology) *Dental Care for Chronically Ill Diabetes Mellitus Female Human *HIV Infections HIV Seronegativity HIV Seropositivity Logistic Models Male Odds Ratio Retrospective Studies Risk Factors Severity of Illness Index Smoking Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Tooth Extraction/*ADVERSE EFFECTS JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).