Document 0623
 DOCN  M9480623
 TI    Rhodococcus equi: first case in a heart transplant recipient.
 DT    9410
 AU    Segovia J; Pulpon LA; Crespo MG; Daza R; Rodriguez JC; Rubio A; Serrano
       S; Carreno MC; Varela A; Aranguena R; et al; Heart Transplant Unit,
       Clinica Puerta de Hierro, Madrid, Spain.
 SO    J Heart Lung Transplant. 1994 Mar-Apr;13(2):332-5. Unique Identifier :
       AIDSLINE MED/94304903
 AB    Rhodococcus equi is a gram-positive diphtheroid that occasionally
       affects immunocompromised patients, usually causing a chronic
       respiratory infection with cavitating pulmonary opacities on chest
       radiograph that resemble mycobacterial or fungal disease. Etiologic
       diagnosis presents a number of pitfalls, because Rhodococcus equi
       isolates mimic many of the characteristics of other microorganisms more
       familiar to the laboratory staff. The treatment of choice for this
       disease has not yet been established, and its mortality rate is greater
       than 50% in individuals with human immunodeficiency virus and 20% to 25%
       among the remaining patients. We describe here the first case of
       Rhodococcus equi infection in a heart transplant recipient. Clinical
       presentation was typical, and treatment with a sensitivity-based
       combination of antibiotics resulted in resolution of both the clinical
       and radiologic picture.
 DE    Adult  Antibiotics, Combined/THERAPEUTIC USE  Case Report  Heart
       Transplantation/*IMMUNOLOGY  Human  Immunosuppressive
       Agents/ADMINISTRATION & DOSAGE/ADVERSE EFFECTS  Male  Microbial
       Sensitivity Tests  Myocardial Diseases/IMMUNOLOGY/*SURGERY
       Opportunistic Infections/DRUG THERAPY/*IMMUNOLOGY  Pneumonia/*IMMUNOLOGY
       Postoperative Complications/DRUG THERAPY/*IMMUNOLOGY  Rhodococcus
       equi/DRUG EFFECTS/*IMMUNOLOGY  Septicemia/*IMMUNOLOGY  JOURNAL ARTICLE

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