Document 0001
 DOCN  M9490001
 TI    Acute severe rhabdomyolysis in an human immunodeficiency
       virus-seropositive patient associated with rising anti-coxsackie B viral
       titers.
 DT    9411
 AU    Beressi A; Sunheimer RL; Huish S; Finck C; Pincus MR; Department of
       Pathology, SUNY Health Science Center, Syracuse; 13210.
 SO    Ann Clin Lab Sci. 1994 May-Jun;24(3):278-81. Unique Identifier :
       AIDSLINE MED/94324800
 AB    Very recently there have been sporadic reports of polymyositis in
       patients who are positive for human immunodeficiency virus (HIV). The
       cause of this condition has not been documented. Recent evidence has
       been presented which indicates that the Coxsackie B virus may be a
       causative factor. Presentation is made of a patient, a drug abuser who
       was found to be HIV-positive with severe polymyositis manifested by
       generalized muscle weakness and a total serum creatinine kinase that
       reached the unusually high level of > 600,000 U/L. This patient was
       found to have a rise in titer of Coxsackie B-4 virus antibodies. He was
       negative for a variety of possible infectious causes of this condition
       and was negative for both antinuclear antibodies (ANA) and rheumatoid
       factor (RF). It is concluded that a polymyositis may indeed be
       associated with immunosuppressed states and that Coxsackie B-4 virus may
       be an important causative factor.
 DE    Adult  Antibodies, Viral/*BLOOD  Case Report  Coxsackievirus
       Infections/*COMPLICATIONS  Coxsackieviruses B/*IMMUNOLOGY  Human  HIV
       Seropositivity/*COMPLICATIONS  Male  Rhabdomyolysis/*COMPLICATIONS
       Substance Abuse  JOURNAL ARTICLE

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