Document 0090
 DOCN  M9490090
 TI    The incidence of the human immunodeficiency virus in injured patients in
       Lusaka.
 DT    9411
 AU    Kehoe NJ; Jellis JE; University Teaching Hospital, Lusaka, Zambia.
 SO    Injury. 1994 Aug;25(6):375-8. Unique Identifier : AIDSLINE MED/94321054
 AB    Patients may present with pathology that is not directly related to
       their primary complaint. The possibility of the presence of an infecting
       agent may not be considered and precautions that should be taken may be
       inappropriately forsaken. A multispecialty study is being undertaken at
       the University of Zambia to assess the influence of the human
       immunodeficiency virus (HIV) on the presentation, treatment and outcome
       of surgical pathology. This study examines the HIV status of 100
       patients presenting through the Accident Department with long bone
       fractures. Assessment using the World Health Organization (WHO) clinical
       staging system for HIV disease has been compared with the patient's
       response to the potential immunological challenge and HIV serological
       status. Thirty-two per cent of adults in the age range 16-55 years were
       seropositive for HIV but this rose to 50 per cent in those aged between
       21 and 40 years. The majority of patients were male, but both sexes had
       similar patterns of serological status. All patients were in WHO stage
       0, 1 or 2 but assessment with the WHO clinical criteria alone led to a
       high level of diagnostic inaccuracy. Clinical assessment of 18 patients
       suggested freedom from HIV influence but their serum was seropositive on
       ELISA testing. The absolute lymphocyte count was below 2000 cells/mm3 in
       patients found to be seropositive and with disease of clinical stage 1
       or 2.
 DE    Adolescence  Adult  Age Factors  Female
       Fractures/*COMPLICATIONS/IMMUNOLOGY/SURGERY  Human  HIV
       Infections/*COMPLICATIONS/IMMUNOLOGY  *HIV Seroprevalence  *HIV-1
       Leukocyte Count  Lymphocytes/CYTOLOGY  Male  Middle Age  Sex Factors
       Support, Non-U.S. Gov't  Zambia/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).