Document 0119
 DOCN  M9490119
 TI    AIDS-free survival and overall survival in HIV infection: the new CDC
       classification system (1993) for HIV disease and AIDS.
 DT    9411
 AU    Kamps BS; Brodt HR; Staszewski S; Bergmann L; Helm EB; Medizinische
       Klinik III, Universitatsklinik Frankfurt, Germany.
 SO    Clin Investig. 1994 Mar;72(4):283-7. Unique Identifier : AIDSLINE
       MED/94319111
 AB    The clinical history of 1538 HIV positive patients was analyzed on the
       basis of the new CDC classification system of HIV disease and AIDS. This
       classification system combines three CD4 cell categories (1, 2, and 3)
       with three clinical categories (A, B, and C) into nine subgroups A1-C3.
       We examined the overall survival for all subgroups and the AIDS-free
       survival for subgroups A1-B3. AIDS-free survival for patients in
       subgroups A1, A2, and B1 was considerably longer than survival in
       patients from subgroups A3, B2, and B3 (P < 0.0001). According to these
       findings, the new CDC classification system could be simplified into
       three stages, stage I and II comprising the above mentioned six
       subgroups, and stage III comprising clinical AIDS defining categories
       C1, C2, and C3. These three stages correspond to different periods in
       the management of HIV positive patients, i.e., period of observation,
       period of prophylaxis, and period of treatment.
 DE    Acquired Immunodeficiency Syndrome/*CLASSIFICATION  Centers for Disease
       Control and Prevention (U.S.)  Human  HIV
       Infections/*CLASSIFICATION/MORTALITY  Prognosis  Survival Analysis
       United States  JOURNAL ARTICLE

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