Document 0516 DOCN M9490516 TI Possible significance of antibodies to Legionella pneumophila in HIV-1 infected patients with acute respiratory illness. DT 9411 AU Del Prete R; Mosca A; Locaputo S; Federico M; Angarano G; Miragliotta G; Institute of Microbiology, University of Bari, Italy. SO Acta Virol. 1994 Feb;38(1):31-3. Unique Identifier : AIDSLINE MED/94346338 AB Eighty-six serum samples from 52 HIV-1 infected patients with complicating pneumonia illness were assayed for the presence of antibodies to Legionella pneumophila. In 25 of these patients Pneumocystic carinii has been previously diagnosed. Among all patients investigated only 4 had antibodies to L. pneumophila of significant titer of 128. In one patient L. pneumophila was demonstrated coexisting with P. carinii. Despite of a small proportion of patients with a significant titer of antibodies against L. pneumophila, the presence of this microorganism should be carefully investigated in AIDS patients with complicating pneumonia especially when the aetiological diagnosis is not defined; the reason is to improve the therapeutic treatment. DE Antibodies, Bacterial/*BLOOD *AIDS-Related Opportunistic Infections/IMMUNOLOGY Human *HIV-1 Legionella pneumophila/*IMMUNOLOGY *Legionnaires' Disease/IMMUNOLOGY Pneumonia, Pneumocystis carinii JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).