Document 0531
 DOCN  M9490531
 TI    [Pneumocystis carinii pneumonia in HIV-infected patients examined by
       bronchoscopy during the period 1989-1991]
 DT    9411
 AU    Jensen AM; Lundgren JD; Nielsen TL; Benfield TL; Vestbo J;
       Infektionsmedicinsk afdeling, Hvidovre Hospital, Kobenhavn.
 SO    Ugeskr Laeger. 1994 Jul 18;156(29):4241-4. Unique Identifier : AIDSLINE
       MED/94345916
 AB    We analyzed prospectively collected data from 211 HIV-infected patients
       who underwent bronchoscopy because of pulmonary symptoms during the
       period 1989-1991. We found an improvement in survival for patients
       diagnosed with Pneumocystis carinii pneumonia (PCP) in 1991 as compared
       to 1989 and 1990 (log rank test: p = 0.07). A significant decline in PO2
       and CD4 cell count was observed in patients with PCP in the same period
       (p < 0.05 and 0.005 respectively). We suggest that the decline in CD4
       cell count and in PO2 may reflect a change in Pneumocystis carinii
       transmission, and that the improved survival may be a result of altered
       treatment strategy of PCP.
 DE    Antigens, CD4/ANALYSIS  AIDS-Related Opportunistic
       Infections/*DIAGNOSIS/IMMUNOLOGY/  MORTALITY  Bronchoscopy  English
       Abstract  Female  Human  HIV Infections/*DIAGNOSIS/IMMUNOLOGY  Male
       Pneumonia, Pneumocystis carinii/*DIAGNOSIS/IMMUNOLOGY/MORTALITY
       Prognosis  Prospective Studies  Support, Non-U.S. Gov't  JOURNAL ARTICLE

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