Document 0534 DOCN M9490534 TI [The immunological manifestations and cytological characteristics of infection caused by the simian immunodeficiency virus (SIV) in rhesus monkeys] DT 9411 AU Persidskii IuV; Shcherbinskaia AM; Barshtein IuA; Antonenko SV; Marichev IL SO Tsitol Genet. 1993 Nov-Dec;27(6):97-104. Unique Identifier : AIDSLINE MED/94345797 AB The results of immunological and morphological studies of Asian macaques (Macaca mulatta) infected by simian immunodeficiency virus (SIV) are summarized in this review of literature. This virus causes development of the immunodeficiency disease that closely resembles human AIDS. Immunological parameters (CD count, antibody response etc.) are described promoting prediction of progression of immunodeficiency in monkeys. The morphological features of injury of internal organs indicate that SIV-induced immunodeficiency is the multisystem disease. DE Acquired Immunodeficiency Syndrome/IMMUNOLOGY/PATHOLOGY Animal Disease Models, Animal English Abstract HIV Infections/IMMUNOLOGY/PATHOLOGY HIV-1 HIV-2 *Macaca mulatta Monkey Diseases/*IMMUNOLOGY/PATHOLOGY Simian Acquired Immunodeficiency Syndrome/*IMMUNOLOGY/PATHOLOGY *SIV JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).