Document 0586 DOCN M9490586 TI Comparison of HIV antibody profiles in intravenous drug users and individuals infected by the sexual route. DT 9411 AU Subramaniam S; Balasubramaniam V; Sinniah M; Thayan R; Lim LY; Division of Virology, Institute for Medical Research, Kuala; Lumpur, Malaysia. SO Malays J Pathol. 1993 Dec;15(2):143-6. Unique Identifier : AIDSLINE MED/94343879 AB HIV-1 antibody patterns in two groups, those infected by the intravenous route (IV drug users) and those infected by the sexual route (prostitutes, male homosexuals and sexually transmitted disease patients) were compared using the Western blot technique. A total of 160 cases were studied. The intravenous drug user (IVDU) group appeared to respond to fewer antibody markers than the sexually infected group, the difference being significant for markers p31, p51, p55, p66, gp41 and gp120. Furthermore, a higher proportion (63%) of the sexually infected group carried antibodies to all Western blot markers as compared to the IVDU group (49%). DE Acquired Immunodeficiency Syndrome/*IMMUNOLOGY/*TRANSMISSION Comparative Study Female Human HIV Antibodies/*BLOOD HIV-1/*IMMUNOLOGY/PHYSIOLOGY Male *Substance Abuse, Intravenous JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).