Document 0640 DOCN M9490640 TI [Obstetrical management of a patient with HIV infection] DT 9411 AU Figueroa Damian R; Departamento de Infectologia e Inmunologia, Instituto Nacional; de Perinatologia, Mexico, D.F. SO Ginecol Obstet Mex. 1994 Jul;62:211-6. Unique Identifier : AIDSLINE MED/94341658 AB In light of the increasing Human Immunodeficiency Virus (HIV) infection in women, the role of the obstetricians-gynecologists in the management of the HIV seropositive patients should increase, for these reasons is needed to improve their knowledge about HIV infection. The perinatal transmission are the principal route of infection in children, prospective studies have informed a maternal-fetal transmission rate between 25 to 35%. HIV may be transmitted to an infant via the placenta. Caesarean delivery appears to play little o no role in preventing neonatal disease. Diverse studies suggest that rates of perinatal transmission may be increased in women with CD4 counts of less than 400/mm3, and in women in the later stages of illness. Pregnant women whose CD4 counts are less than 500/mm3 should receive zidovudine, preferably beyond the first trimester. All the health care workers must rigorously follow the recommendations for minimizing the risk of occupational transmission of HIV. DE Acquired Immunodeficiency Syndrome/DRUG THERAPY/EPIDEMIOLOGY/ *TRANSMISSION Adult English Abstract Female Human HIV Infections/DRUG THERAPY/EPIDEMIOLOGY/*TRANSMISSION Maternal-Fetal Exchange Mexico/EPIDEMIOLOGY Pregnancy Pregnancy Complications, Infectious Pregnancy Outcome Pregnancy Trimester, Second Pregnancy Trimester, Third Zidovudine/*ADMINISTRATION & DOSAGE JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).