Document 0702
 DOCN  M9490702
 TI    Antibiotic chemotherapy of bacterial sexually transmitted diseases in
       adults: a review.
 DT    9411
 AU    Corcoran GD; Ridgway GL; Department of Clinical Microbiology, University
       College London; Hospitals, UK.
 SO    Int J STD AIDS. 1994 May-Jun;5(3):165-71. Unique Identifier : AIDSLINE
       MED/94339217
 AB    Treatment regimens for sexually transmitted infections continue to
       evolve. The natural history of syphilis in HIV-infected patients is
       leading to more aggressive policies in terms of both investigation and
       treatment. In particular, treatment protocols for late syphilis,
       especially neurosyphilis, are under scrutiny. Epidemiological change
       typified by the spread of penicillinase-producing Neisseria gonorrhoeae
       (PPNG) has led to a search for new agents to treat gonorrhoea, with a
       more extensive use of cephalosporin and quinolone antibiotics emerging.
       The problem of compliance with the antibiotic courses presently required
       for chlamydial infection may be close to being solved with the
       development of newer macrolide agents. Single dose azithromycin,
       although expensive, seems to be as effective as longer courses with
       other agents. Furthermore, its efficacy in gonococcal infection is also
       encouraging. Increased understanding of the pathogenesis and natural
       history of pelvic inflammatory disease (PID) and bacterial vaginosis
       (BV) has led to rationalization of treatment policies for these
       conditions.
 DE    Adnexitis/DRUG THERAPY  Adult  Antibiotics/*THERAPEUTIC USE  Female
       Gonorrhea/DRUG THERAPY  Human  HIV Infections/COMPLICATIONS  Male
       Pregnancy  Pregnancy Complications, Infectious/DRUG THERAPY  Sexually
       Transmitted Diseases, Bacterial/*DRUG THERAPY
       Syphilis/COMPLICATIONS/DRUG THERAPY  Urethritis/DRUG THERAPY  Vaginosis,
       Bacterial/DRUG THERAPY  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).