Document 0016
 DOCN  M94A0016
 TI    Sequence variation in the gp135 gene of Maedi visna virus strain EV1.
 DT    9412
 AU    Carey N; Dalziel RG; Department of Veterinary Pathology, University of
       Edinburgh,; Summerhall.
 SO    Virus Genes. 1994 Mar;8(2):115-23. Unique Identifier : AIDSLINE
       MED/94353637
 AB    We have used the PCR and HIRT DNA obtained from MVV-infected tissue
       culture cells as a template to generate a number of independently
       derived clones representing overlapping fragments of the gp135 region
       (env) of Maedi visna virus (MVV) strain EV1. Sequencing these clones
       revealed that homology between selected regions of gp135 ranged from
       93.2% to 99.8%. Four hypervariable regions and one large highly
       conserved region have been identified. These data provide information on
       the variability of EV1 env, which extends and complements the data
       previously available on env variability between geographically distinct
       isolates of MVV.
 DE    Amino Acid Sequence  Base Sequence  Cloning, Molecular  Genes,
       env/*GENETICS  Molecular Sequence Data  Sequence Analysis, DNA  Sequence
       Homology, Amino Acid  Variation (Genetics)/*GENETICS  Viral Envelope
       Proteins/*GENETICS  Visna-Maedi Virus/*GENETICS  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).