Document 0078
 DOCN  M94A0078
 TI    Improved body weight status as a result of nutrition intervention in
       adult, HIV-positive outpatients.
 DT    9412
 AU    McKinley MJ; Goodman-Block J; Lesser ML; Salbe AD; Center for Special
       Studies, New York Hospital, NY.
 SO    J Am Diet Assoc. 1994 Sep;94(9):1014-7. Unique Identifier : AIDSLINE
       MED/94351121
 AB    OBJECTIVE: Malnutrition is an important consequence of infection with
       the human immunodeficiency virus (HIV); involuntary weight loss greater
       than 10% is one criterion that the Centers for Disease Control and
       Prevention uses for the diagnosis of acquired immunodeficiency syndrome
       (AIDS). This study was designed to determine whether nutrition
       intervention in a group of adult, HIV-positive outpatients affected
       weight maintenance. METHODS: We undertook a retrospective review of 175
       patient charts from the AIDS Reproductive Health Clinic and the Center
       for Special Studies at The New York Hospital. Forty-nine charts were
       excluded because the patient expressed a desire to reduce weight,
       discontinued medical care, or died. Seven charts were eliminated because
       of missing data. In the remaining patients (n = 119), weights were
       recorded for the initial clinic contact and for a follow-up visit at
       least 6 months later. Nutrition intervention completed by a registered
       dietitian was indicated on 42 patient charts (intervention group);
       intervention included dietary assessment, intake analysis, appropriate
       counselling, follow-up, and provision of supplements as needed. The
       remaining 77 charts did not indicate nutrition intervention; this group
       was called the nonintervention group. Differences between the
       intervention and nonintervention groups were analyzed using the
       two-tailed Fisher exact test and the Mann-Whitney nonparametric test.
       RESULTS: Forty-two subjects (35% of the total) recieved nutrition
       intervention, including all of those with gastrointestinal problems (n =
       10) and wasting (n = 11). Individuals in the intervention group gained a
       significant (P < .02) 1.2 +/- 11.4 lb (mean +/- standard deviation;
       median = +3 lb) compared with those in the nonintervention group who
       lost a mean of 3.5 +/- 12.8 lb (median = -4 lb). Twenty-six subjects
       (63%) in the intervention group maintained or gained weight compared
       with 32 subjects (42%), in the nonintervention group. CONCLUSION: The
       results of this study suggest that nutrition intervention in
       HIV-infected persons can improve nutritional status and may lead to an
       enhanced ability to fight infection.
 DE    Adult  *Body Weight  Emaciation/COMPLICATIONS  Female  Follow-Up Studies
       Gastrointestinal Diseases/COMPLICATIONS  Human  HIV
       Infections/COMPLICATIONS/*DIET THERAPY  Leukocyte Count  Male  Middle
       Age  Nutrition Disorders/*PREVENTION & CONTROL  Pneumonia, Pneumocystis
       carinii/COMPLICATIONS  Retrospective Studies  Support, U.S. Gov't,
       P.H.S.  Syndrome  T4 Lymphocytes  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).