Document 0132
 DOCN  M94A0132
 TI    Risk factors for HIV-1 seroprevalence among drug injectors in the
       cocaine-using environment of Rio de Janeiro.
 DT    9412
 AU    Lima ES; Friedman SR; Bastos FI; Telles PR; Friedmann P; Ward TP; des
       Jarlais DC; Nucleo de Estudos e Pesquisas em Atencao ao Uso de Drogas;
       (NEPAD), Rio de Janeiro, Brazil.
 SO    Addiction. 1994 Jun;89(6):689-98. Unique Identifier : AIDSLINE
       MED/94348362
 AB    To determine risk factors for HIV-1 among drug injectors in Rio de
       Janeiro, where cocaine is the dominant drug of injection, subjects were
       recruited using the criteria and interview instrument of the World
       Health Organization's Cross-National Study of HIV infection and risk
       behaviour in injecting drug users. HIV antibody test results were
       derived both from serum tests and from self-reports of previous tests
       (documented evidence of self-reported seropositivity was required). The
       analytical sample consists of 123 subjects, recruited both at drug abuse
       treatment sites and at street locations. Of 27 subjects with both
       serological and self-reported antibody status data, 20 reported previous
       negative tests; of these three had positive sera and may have
       seroconverted. Seven subjects reporting prior positive serostatus all
       tested positive. For the 123 subjects, seroprevalence was 34%.
       Independent significant risk factors in multivariate logistic regression
       with backwards elimination are: years of injection greater than 5; being
       a male who has had sex with men in the previous 5 years; and not having
       taken deliberate steps to protect oneself against AIDS. These findings
       indicate that homosexual/bisexual male drug injectors may be a bridge
       group through which HIV is entering drug-injecting networks in Rio de
       Janeiro. Efforts by drug injectors to reduce their risk of infection
       seem to have protective effects. This underscores the importance of HIV
       prevention efforts aimed at drug injectors.
 DE    Brazil/EPIDEMIOLOGY  *Cocaine  Comorbidity  HIV
       Seropositivity/COMPLICATIONS/DIAGNOSIS/*EPIDEMIOLOGY  *HIV-1  Risk
       Factors  Self Assessment (Psychology)  Substance Abuse,
       Intravenous/*COMPLICATIONS  Support, Non-U.S. Gov't  Support, U.S.
       Gov't, P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).