Document 0157
 DOCN  M94A0157
 TI    Recent developments in psoriatic arthritis.
 DT    9412
 AU    Cuellar ML; Silveira LH; Espinoza LR; Section of Rheumatology, LSU
       Medical Center, New Orleans; 70112-2822.
 SO    Curr Opin Rheumatol. 1994 Jul;6(4):378-84. Unique Identifier : AIDSLINE
       MED/94347567
 AB    Psoriatic arthritis affects 5% to 7% of patients with psoriasis.
       Genetic, immunologic, and environmental factors play a role in its
       pathogenesis. The role of inflammatory cytokines has been better
       defined, and recent immunohistochemical studies of the synovial
       membranes have shown important differences and similarities between
       psoriatic arthritis and rheumatoid arthritis. The association of
       psoriatic arthritis with infection, particularly HIV, remains an
       interesting observation. The most common clinical presentation appears
       to be peripheral polyarticular, and extra-articular manifestations
       including the SAPHO (synovitis, acne, pustulosis, hypertosis, and
       osteitis) syndrome are not common. Methotrexate and sulfasalazine
       therapy are effective in patients who do not respond to nonsteroidal
       anti-inflammatory drugs.
 DE    *Arthritis, Psoriatic/DIAGNOSIS/EPIDEMIOLOGY/ETIOLOGY/THERAPY  Human
       JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

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