Document 0158
 DOCN  M94A0158
 TI    Case report: the effect of a Chinese herbal medicine, BG-104 in two HIV
       positive hemophiliacs.
 DT    9412
 AU    Arimori S; Nozaki H; Morita K; Arimori K; Tokai University Medical and
       Health Care Administration Center,; Isehara, Japan.
 SO    Biotherapy. 1993;7(1):55-7. Unique Identifier : AIDSLINE MED/94347539
 AB    The BG-104, a Chinese herbal medicine, has been reported to restore
       decreased plasma superoxide scavenging activity. This report showed in
       vivo effect of BG-104 on two patients with hemophilia A infected with
       human immunodeficiency virus by infusions of the concentrated Factor
       VIII. Both patients, showed a peripheral CD4+ T-lymphocytopenia for more
       than half a year. BG-104 was administered daily and follow-up
       observations were continued for 3 years. The number of CD4+
       T-lymphocytes remained relatively constant during BG-104 treatment
       without disease progression.
 DE    Adult  Antigens, CD8/ANALYSIS  Antioxidants/*THERAPEUTIC USE  Case
       Report  Drugs, Chinese Herbal/*THERAPEUTIC USE  Flow Cytometry
       Follow-Up Studies  Free Radical Scavengers
       Hemophilia/BLOOD/COMPLICATIONS/*DRUG THERAPY/*MICROBIOLOGY  Human  HIV
       Seropositivity/COMPLICATIONS/*DRUG THERAPY  Leukocyte Count  Male
       T-Lymphocytes/IMMUNOLOGY  T-Lymphocytopenia, Idiopathic
       CD4-Positive/PREVENTION & CONTROL  T4 Lymphocytes  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).