Document 0199
 DOCN  M94A0199
 TI    Anaerobic flora of the conjunctival sac in patients with AIDS and with
       anophthalmia compared with normal eyes.
 DT    9412
 AU    Campos MS; Campos e Silva L de Q; Rehder JR; Lee MB; O'Brien T;
       McDonnell PJ; Department of Ophthalmology, Paulista School of Medicine,
       Sao; Paulo, Brazil.
 SO    Acta Ophthalmol (Copenh). 1994 Apr;72(2):241-5. Unique Identifier :
       AIDSLINE MED/94360750
 AB    Relatively few investigations of anaerobic bacteria as ocular flora have
       been conducted, and their results have been contradictory. The
       conjunctival sacs of 22 normal subjects and of 14 patients with acquired
       immunodeficiency syndrome, and 22 anophthalmic sockets were cultured for
       anaerobic bacteria Thirty-four (77.3%) of the 44 eyes of normal subjects
       harbored anaerobic bacteria; Propionibacterium acnes was present in 28
       eyes (63.6%), Lactobacillus species in 6 eyes (13.6%), and Veillonella
       species in 7 eyes (15.9%). The finding were very similar for
       anophthalmic sockets (p = 0.01), with 17 (77.3%) of the 22 sockets
       harboring anaerobes; Propionibacterium acnes was the organism identified
       in 16 (72.7%) of these sockets; Veillonella was identified in 4 (18.1%),
       Peptococcus niger in 3 (13.6%) and P. granulosum in 2 (9.0%) of these
       sockets. Acquired immunodeficiency syndrome patients had the highest
       incidence of anaerobic organisms, with positive cultures obtained from
       24 (85.7%) of the 28 eyes. Propionibacterium species were isolated from
       16 (57.1%) of these eyes. Clostridium species from 10 (35.7%) eyes and
       Actinomyces species from 8 (28.6%) eyes. It thus appears that anaerobic
       organisms are common flora in normal conjunctival sacs and in
       anophthalmic sockets, as well as in the sacs of acquired
       immunodeficiency syndrome patients, but the latter group had a higher
       incidence (x2 = 0.87) and a spectrum of organisms that was different
       from that of the other two groups.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/*MICROBIOLOGY  Adult
       Aged  Aged, 80 and over  Anophthalmos/COMPLICATIONS/*MICROBIOLOGY
       Bacteria, Anaerobic/*ISOLATION & PURIF  Conjunctiva/*MICROBIOLOGY  Human
       Middle Age  Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).