Document 0318
 DOCN  M94A0318
 TI    Oral hairy leukoplakia in a child: confirmation of the clinical
       diagnosis by ultrastructural examination of exfoliative cytologic
       specimens.
 DT    9412
 AU    Itin PH; Bircher AJ; Litzisdorf Y; Rudin C; Department of Dermatology,
       University of Basel, Switzerland.
 SO    Dermatology. 1994;189(2):167-9. Unique Identifier : AIDSLINE
       MED/94355713
 AB    We report on a 12-year-old girl infected with human immunodeficiency
       virus (HIV) who developed oral hairy leukoplakia (OHL). This is the
       fifth child with OHL whose case has been described so far. The clinical
       diagnosis was confirmed by ultrastructural documentation of a
       herpes-type virus in the lesional scraping specimen. Exfoliative
       material was obtained by a painless and noninvasive procedure. We
       conclude that ultrastructural examination of lingual exfoliative
       cytological specimens from clinically suspected OHL is a noninvasive and
       painless method for confirming the clinical diagnosis of OHL.
 DE    Biopsy/METHODS  Case Report  Child  Female  Herpesviridae
       Infections/COMPLICATIONS/MICROBIOLOGY/*PATHOLOGY  Herpesvirus 4,
       Human/ISOLATION & PURIF  Human  HIV Infections/*COMPLICATIONS
       Leukoplakia, Oral/COMPLICATIONS/MICROBIOLOGY/*PATHOLOGY/
       *ULTRASTRUCTURE  Microscopy, Electron  Tongue/*PATHOLOGY/ULTRASTRUCTURE
       Tumor Virus Infections/COMPLICATIONS/MICROBIOLOGY/*PATHOLOGY  JOURNAL
       ARTICLE

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