Document 0696 DOCN M94A0696 TI HIV-related mycobacterial infections in Queensland. DT 9412 AU Konstantinos A; Dawson D; Patel AM; Mycobacterial Reference Laboratory, Queensland Health, Brisbane. SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:33 (abstract no. FC3). Unique Identifier : AIDSLINE ASHM5/94348959 AB Human Immunodeficiency Virus (HIV) related mycobacterial infections in Queensland (Qld) were studied to define which mycobacteria contribute to HIV-related disease in Qld and implications for management. Mycobacteria were isolated from 112 HIV patients in Qld from 1/7/85-22/1/93 (Mycobacterium tuberculosis complex [MTBC] in 7 and atypical mycobacteria [ATM] in 105). 94 of 108 ATM isolates in the latter were M.avium complex (MAC) (75 M.avium and 19 M.intracellulare) with different serotypes often isolated from different sites in the same patient. HIV associated MTBC infection is not yet a problem in Qld. As most non HIV-related MAC infections Qld in the past were M.intracellulare, the predominance of M.avium infections in this study suggests that either HIV patients are particularly susceptible to M.avium infection, or there has been a recent shift in the mycobacterial population as supported by a recent increase in M.avium isolates from lymph nodes in non HIV-infected Qld children. Further evaluation of the role of different MAC serotypes in significant disease requires prospective study. DE Adult AIDS-Related Opportunistic Infections/DIAGNOSIS/*EPIDEMIOLOGY Child Cross-Sectional Studies Human Incidence Mycobacterium avium-intracellulare Infection/DIAGNOSIS/ *EPIDEMIOLOGY Queensland/EPIDEMIOLOGY Tuberculosis, Pulmonary/DIAGNOSIS/*EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).