Document 0910
 DOCN  M94A0910
 TI    Prevalence of anti-HIV, p24 antigen and other markers in blood donors.
 DT    9412
 AU    Kamtom N; Mundee Y; Chaiyaphruk S; Nanthachit N; Ness P; Nelson KE;
       Chiang Mai University, Thailand.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):252 (abstract no. PC0373). Unique
       Identifier : AIDSLINE ICA10/94371665
 AB    OBJECTIVE: To evaluate the recent trends in the prevalence of anti-HIV
       and p24 antigen among different types of blood donors in Chiang Mai,
       Thailand. METHODS: All blood donors were screened for anti-HIV in Chiang
       Mai since February, 1988. Because of increasing anti-HIV prevalence, the
       p24 antigen screening was begun in April, 1992 and confirmed with
       neutralization test. All donors were also screened for STS, HBsAg and
       anti-HIV. The prevalence of anti-HIV by type of donor is shown,
       1988-1993. Donors were classed as professional (paid), replacement
       (relative) and volunteer (red cross). The professional donation was
       abolished on July, 1992. RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. In
       1992, 25 of 18252 (0.14%) donors were positive p24 antigen. 14 of 25
       (0.077%) were positive both anti-HIV and p24 antigen. 11 of 25 (0.060%)
       were positive p24 antigen but negative ant-HIV, 8 of 11 (0.044%) were
       not confirmed by neutralization test, but 3 of 11 (0.016%) were
       confirmed. CONCLUSION: The prevalence of all types of donor increased
       rapidly in 1989 and continued to climb year after year. Stopping of paid
       donation and screening for p24 antigen can increase the safety of blood
       and blood products. However, more effective donor exclusion and donor
       self selection strategies are needed in the populations with major
       heterosexual HIV epidemics.
 DE    Biological Markers/*ANALYSIS  *Blood Donors  Human  HIV
       Antibodies/*ANALYSIS  HIV Core Protein p24/*ANALYSIS  *HIV
       Seroprevalence  Thailand/EPIDEMIOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).