Document 2406
 DOCN  M94A2406
 TI    Prevalence of non-progression of immunodeficiency in women with HIV
       infection.
 DT    9412
 AU    Carpenter CC; Flanigan TP; Mayer KH; Brown University, Providence, RI
       02906.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):311 (abstract no. PC0175). Unique
       Identifier : AIDSLINE ICA10/94370169
 AB    OBJECTIVE: To determine the prevalence of non-progression of
       immunodeficiency in North American women with HIV infection. METHODS: 94
       asymptomatic women living with HIV infection were followed closely for
       periods of 3 to 7 yr (mean 4.1 yr). All had initial CD4 counts > 200
       cells/mm3. Patients had CD4 counts at 6 month intervals. Intercurrent
       health problems were treated by standard regimens. 29% of women acquired
       HIV via sex, 71% via injecting drug use. Ethnic backgrounds were:
       Caucasian 68%; African-American 20%, Latina 12%. RESULTS: The median
       change in CD4 count was -50 cells/yr (range -477 to +73). 25 women had
       decreases in CD4 counts less than 15 cells/yr. All 25 remained
       asymptomatic, and their mean CD4 count increased by 14 cells per/yr. 7
       of the 25 women had documented HIV infection for over 6 yr. Ethnic
       backgrounds and modes of transmission did not differ from those in the
       69 women whose CD4 counts fell at a greater rate. DISCUSSION &
       CONCLUSIONS: 27% of 94 women with HIV infection showed no decline of CD4
       count and no symptoms related to immunodeficiency over a 3 to 7 yr
       period. The data indicate that long periods of immunologic stability are
       not uncommon among HIV-infected women.
 DE    Female  Follow-Up Studies  Human  HIV Infections/*IMMUNOLOGY  Leukocyte
       Count  T4 Lymphocytes  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).