Document 2410
 DOCN  M94A2410
 TI    Infants born from HIV+ mothers.
 DT    9412
 AU    Rimoldi I; Avolio J; Arreseigor T; Provincial Ref. Center for AIDS, La
       Plata, Argentina.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):310 (abstract no. PC0168). Unique
       Identifier : AIDSLINE ICA10/94370165
 AB    OBJECTIVE: To describe and to evaluate results obtained in our
       Laboratory from serum samples of infants born from seropositive mothers
       in Buenos Aires, Argentina. METHODS: 18 month follow-up using
       serological techniques: EIA or PA--WB and EIA(Ag)--HIV antigen
       confirmation. Licensed kits were used. RESULTS: 489 serum samples of 306
       infants born from HIV seropositive mothers were received from Jan. 1989
       through Dec. 1993 (1989 = 32, 1990 = 43, 1991 = 66, 1992 = 88, 1993 =
       77). 69 (22.5%) have completed the follow-up; 30 of them (43.5%)
       remained seropositive, 32 (46.4%) seroreverted, and 7 (10.1%) were
       undetermined (p-24 band was still present after long term follow-up). 52
       infants are still under follow-up. 169 (55.4%) were lost and their
       present status is unknown; 42 were HIV+ at first sample, presenting
       clinical symptoms of AIDS while their mothers' HIV+ status were unknown;
       31 were elder than 18 months, and 11 were under 12 months, being
       serological diagnosis very difficult due to total or partial lose of HIV
       specific antibody. CONCLUSION: 1) hard policies and social service are
       needed for these infants' families to lead an adequate clinical and
       serological follow-up. 2) Early detection of perinatal HIV acquired
       infection is needed to establish the specific therapy as soon as
       possible.
 DE    *AIDS Serodiagnosis  Female  Human  HIV
       Infections/DIAGNOSIS/*TRANSMISSION  *HIV Seropositivity  Infant  Infant,
       Newborn  Pregnancy  *Pregnancy Complications, Infectious  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).