Document 2419
 DOCN  M94A2419
 TI    Ante & post natal HIV screening in Bombay-India.
 DT    9412
 AU    Merchant RH; Gilada IS; Mahajan RP; Agarwal JG; Mehta AC; Wadia
       Maternity Hospital, Parel, Bombay.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):309 (abstract no. PC0165). Unique
       Identifier : AIDSLINE ICA10/94370156
 AB    OBJECTIVE: To determine incidence of HIV antibodies in the antenatal
       population in a large urban city in India and clinically & serologically
       evaluate infants born to those women who tested HIV positive. METHODS:
       Over a 13 month period ending 1994 January, 13,977 pregnant women were
       screened for the presence of HIV antibodies at the Wadia Maternity
       Hospital, Bombay, India. Blood was tested by Rapid Elavia mixt screening
       test for HIV1 and HIV2 antibodies (Sanofi Diagnostics Pasteur-France &
       Genetic Systems Corp USA) by ELISA technique. Infants born to HIV
       positive mothers are being clinically assessed at the 3 monthly
       intervals and will be tested at 6, 12 & 18 months for the presence of
       HIV antibodies. RESULTS: 97 women (.69%) tested positive at the first
       visit, while only 58 came for follow up serotesting, of which 43 have
       delivered to date. All cord blood samples tested (n = 40) were positive
       for HIV antibodies. 52 sexual partners of these 58 women were available
       for testing and 51 tested seropositive. 4 of these 58 women tested
       serologically positive for syphilis, while only one was a commercial sex
       worker. Of 43 who delivered, 39 were live born with mean birth weight of
       2500 gm and mean gestation of 38.2 weeks. No infant had congenital
       malformation. CONCLUSION: To date no infant followed up clinically upto
       6 months post delivery has exhibited clinical evidences to suggest
       active HIV infection. All 12 infants serotested so far at 6 months age
       have tested positive for HIV antibodies. Given the large number of
       deliveries in India (20-22 million per annum), and a prevalence rate of
       approximately 0.7% in the urban population, this disorder poses a major
       problem in the future.
 DE    *AIDS Serodiagnosis  Female  Human  HIV
       Infections/DIAGNOSIS/TRANSMISSION  *HIV Seropositivity  Infant, Newborn
       *Neonatal Screening  Pregnancy  Pregnancy Complications,
       Infectious/*DIAGNOSIS  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).