Document 2421
 DOCN  M94A2421
 TI    Risk factors and characteristics of HIV+ antenatal women, Bangkok,
       Thailand. Bangkok Perinatal HIV Transmission Study.
 DT    9412
 AU    Mangclaviraj Y; Chaisilwattana P; Siriwasin W; Roongpisuthipong A;
       Shaffer N; Rajvithi Hospital, MOPH.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):308 (abstract no. PC0162). Unique
       Identifier : AIDSLINE ICA10/94370154
 AB    OBJECTIVES: To determine risk factors for HIV seropositivity and
       characteristics at study entry of pregnant women registering for
       antenatal care in Bangkok. METHODS: At 2 large hospitals in Bangkok with
       regular antenatal HIV counseling and testing, HIV-infected pregnant
       women are enrolled for prospective followup in a perinatal transmission
       study; HIV-negative control women are enrolled for a single
       questionnaire evaluation to help assess risk factors and characteristics
       associated with HIV seropositivity. RESULTS: Through Dec 1993, 293 HIV+
       and 293 HIV- women were enrolled in antenatal clinic. Compared to HIV-
       women, HIV+ women were younger (22 vs. 24 yrs; p < 0.01) and were more
       likely to have: a history of STD's (20% vs. 4%; p < 0.01); worked as a
       sex worker (8% vs. 1%; p < 0.01); a history of > or = 3 sex partners
       (15% vs. 3%; p < 0.01). However, 80% of HIV+ women and 96% of HIV- women
       had no evident risk factor for HIV infection. The median CD4 count of
       HIV+ women at study entry was 430 (range 100-1290); 2% of women had CD4
       counts < 200 and 66% had CD4 counts < 500. HIV+ women reported
       significantly more symptoms of weight loss (13% vs. 4%), fatigue (11%
       vs. 1%), and vaginal candidiasis (32% vs. 17%) than HIV- women. None of
       the HIV+ women had signs of AIDS. Enrollment and risk factor analyses
       are ongoing. CONCLUSIONS: Most HIV+ women presenting to antenatal care
       did not have recognizable risk factors for HIV infection. While most
       HIV+ women were asymptomatic, consistent with a recent and rapidly
       expanding epidemic, immunosuppression, as assessed by CD4 counts, was
       higher than expected.
 DE    Adult  Female  Human  HIV Infections/DIAGNOSIS  *HIV Seropositivity
       Pregnancy  *Pregnancy Complications, Infectious/DIAGNOSIS  Risk Factors
       Thailand  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).