Document 2425
 DOCN  M94A2425
 TI    Risks of bottle-feeding in infants born to HIV-infected mothers from
       low-income families in Rio de Janeiro-Brazil.
 DT    9412
 AU    Rubini NP; Silva WA; Sion FS; Morais-De-Sa CA; Lima AJ; Rocco R; Gaffree
       & Guinle Hospital-University of Rio de Janeiro.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):307 (abstract no. PC0158). Unique
       Identifier : AIDSLINE ICA10/94370150
 AB    OBJECTIVE: To evaluate the risk of bottle-feeding to infants born to
       HIV-infected mothers from low-income families. METHODS: Between Jan 89
       and Dec 93 we studied 28 infants born to HIV-infected mothers from with
       a monthly income of 300 US dollars or less submitted to bottle-feeding.
       All the infants were initially HIV-antibody positive but had
       seroreverted to negative and lack evidence of HIV infection by age 18
       months. Commercial milk powder formula was supplied to families and
       mother were taught how to hygienically prepare bottle feed. Medical
       consultation were schedule monthly up to 6 months of age and then
       bimonthly until 18 months. The following parameters were analyzed: 1)
       measurement of weight, height and head circumference, 2) frequency of
       respiratory and gastrointestinal infections, and 3) the need for
       hospitalizations. RESULTS: All births were to term and birthweight
       varied from 2330g to 4440g (mean = 3159 +/- 215). Monthly family income
       varied from 100 to 300 US dollars (mean = 163 +/- 28). Mean annual
       frequency of infectious episodes was 2.1 +/- 0.7 (1-5) for respiratory
       and 1.3 +/- 0.4 (1-2) for gastrointestinal diseases. Two patients needed
       hospitalization: one for a bacterial pneumonia and the other for viral
       gastroenteritis. Both did well and recovered. Malnutrition was not
       reported. No deaths were observed. CONCLUSIONS: 1) In this study
       bottle-feeding in infants born to HIV-infected mothers from low-income
       families was not associated with malnutrition nor increased frequency of
       infectious diseases. 2) Programs of bottle-feeding for infants born to
       HIV-infected mothers, with free distribution of the milk formula and
       mother's instruction about the hygienical prepare may be a useful tool
       to decrease vertical HIV transmission in developing countries.
 DE    *Bottle Feeding/ADVERSE EFFECTS  Female  Human  HIV
       Infections/*PREVENTION & CONTROL/TRANSMISSION  Infant  Infant Nutrition
       Infant, Newborn  Poverty  Pregnancy  *Pregnancy Complications,
       Infectious  Risk Factors  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).