Document 2426 DOCN M94A2426 TI Risk factors for perinatal transmission in HIV positive pregnant women. DT 9412 AU Soriano RM; Carreras R; Rovira MT; Torrent A; Paya A; Xercavins J; Dept. Obstetrics and Gynecology, Autononus University of; Barcelona, Del Mar Hospital, Spain. SO Int Conf AIDS. 1994 Aug 7-12;10(1):307 (abstract no. PC0156). Unique Identifier : AIDSLINE ICA10/94370149 AB GOAL: Analysis of risk factors that could be influential in HIV perinatal transmission. PATIENTS AND METHODS: We have studied 172 HIV positive pregnant women between 1985 and 1993. Perinatal Transmission and factors that could be influential, such as disease stage, maternal risk factors for HIV infection, accompanying obstetrics pathology, mechanism and type of delivery, were studied. RESULTS: HIV perinatal transmission rate after 18 months follow up was 14%: We have not found statistical significant difference among different mechanisms of maternal infection. In mothers with positive HIV antigens during pregnancy a transmission rate of 68% was observed, which is statistically significantly different to the HIV antigen negative mothers transmission rate. (text not legible). CONCLUSION: Perinatal Transmission rate in our population was 14%. Mother's risk factors for HIV transmission, as well as disease stage and CD4 count do not have a statistical significant influence in perinatal transmission rate. Neither there are differences as to obstetric pathology, mechanism and type of delivery. Mothers with HIV antigens during pregnancy show a higher of vertical transmission. DE Female Human HIV Antigens/ANALYSIS HIV Infections/IMMUNOLOGY/*TRANSMISSION Infant, Newborn Pregnancy *Pregnancy Complications, Infectious/IMMUNOLOGY Risk Factors MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).