Document 2466
 DOCN  M94A2466
 TI    HIV-1 risk factors among self-reported heterosexual men in Mexico City:
       controlling for misclassification bias.
 DT    9412
 AU    Fernandez Difranco G; Uribe P; Hernandez MA; Gortmaker S; Harvard School
       of Public Health, Department of Epidemiology,; Boston, MA 02115.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):298 (abstract no. PC0118). Unique
       Identifier : AIDSLINE ICA10/94370109
 AB    OBJECTIVE: To identify risk factors for HIV-1 infection among
       heterosexual (HE) men from Mexico City controlling for potential
       misclassification of sexual orientation. METHODS: From 1990-1992, 4089
       male volunteers were tested for HIV-1 by CONASIDA. Of these, 1926
       self-reported as HE. Double ELISA and a confirmatory Western blot
       identified 147 HIV-1 positive HE and 969 HIV-1 negative homosexuals
       (HO). Risk factors for HIV-1 infection among HE men were evaluated using
       a questionnaire. A multivariate misclassification scale of HE was
       developed based on non-sexual behavior and socio-economic indicators.
       Homosexuality was expected to be under-reported, despite the anonymity
       of the questionnaire, due to the stigma associated with HO behavior in
       Mexican society. RESULTS: Using a scale derived from a multiple
       regression model, we found no evidence of misclassification of HE men.
       The multiple R in this regression was 0.41, indicating moderate
       predictability for identifying individuals who were behaviorally HO vs
       HE. Older age (p = 0.0016), less education (p = 0.0001), report of a
       sexual partner with AIDS (OR = 2.95, p = 0.0026) and blood transfusion
       (OR = 3.78, p = 0.0001) were related to higher risk of HIV-1 infection
       by HE in a multiple logistic regression, controlling for
       misclassification. CONCLUSION: Significant risk factors for HIV-1 were
       found in the sample of HE males from Mexico City with no evidence of
       misclassification.
 DE    AIDS Serodiagnosis  Homosexuality  Human  HIV Infections/*TRANSMISSION
       *HIV-1  Male  Mexico  Risk Factors  *Sex Behavior/CLASSIFICATION
       MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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