Document 2499 DOCN M94A2499 TI Epidemiology of retroviral infections in south India. DT 9412 AU Babu PG; Ishida T; Nerurkar V; John TJ; CMC Hosp, Vellore, India. SO Int Conf AIDS. 1994 Aug 7-12;10(1):290 (abstract no. PC0082). Unique Identifier : AIDSLINE ICA10/94370076 AB OBJECTIVE: To determine time trends of HIV-1, HIV-2, HTLV-I/II and STLV-I infections in Southern India. METHODS: From 1986 onwards, sera collected from persons at high risk and low risk for human retroviral infections, and from 1982 onwards, locally caught bonnet monkeys, were screened for respective antibodies by ELISA/particle agglutination test. Reactive samples were confirmed by Western Blot. PCR and virus cultures were done where necessary. RESULTS: HIV-1 prevalence increased from 2.5% in 1986 to 40% in 1993 in female commercial sex workers, from 0.5% to 5% in male STD patients, and from 0.16% to 0.3% in non-professional blood donors while it remained stable at 0.04% in pregnant women. HIV-2, HTLV-I & II were detected in risk groups in 1990-91. HTLV-I/II has been detected in blood donors in 1994. STLV prevalence ranged from 23% to 44% during the last decade. DISCUSSION AND CONCLUSIONS: HIV-1 infection is spreading rapidly in high risk groups while the spread is slow but steady in low risk groups representative of general population. Other retroviral infections are also prevalent in our region. DE Animal Female Human HIV Infections/*EPIDEMIOLOGY HIV-1 HIV-2 HTLV Infections/*EPIDEMIOLOGY/VETERINARY HTLV-I HTLV-II India/EPIDEMIOLOGY Macaca radiata Male Monkey Diseases/EPIDEMIOLOGY Prevalence Risk Factors STLV MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).