Document 2513 DOCN M94A2513 TI HIV infection in Singapore, 1985-1993. DT 9412 AU Oh HM; Chew SK; Communicable Disease Centre, Singapore. SO Int Conf AIDS. 1994 Aug 7-12;10(1):287 (abstract no. PC0071). Unique Identifier : AIDSLINE ICA10/94370062 AB Human immunodeficiency virus (HIV) infection was first reported in Singapore in 1985 and the first case of the acquired immunodeficiency syndrome (AIDS) was detected in 1986. By the end of 1993, there was a cumulative 222 residents with HIV infection, including 75 cases of AIDS, with a male-to-female ratio of 12:1. The majority of cases were infected through sexual transmission (heterosexual 54%, homosexual 27%, bisexual 12%). Perinatal transmission accounted for 0.5%, intravenous drug use 3%, and infection from receiving contaminated blood and organ transplantation overseas, 2%. Prior to 1990, HIV infection occurred predominantly in homosexuals and bisexuals. After 1990, there was a significant increase in the number of patients infected through heterosexual transmission. Of the first 44 cases, 23% were attributed to heterosexual transmission, compared with 62% for the subsequent 178 cases. The pattern of HIV infection in Singapore can be described as a first wave of infection in homosexual and bisexual men followed by a second wave in heterosexual males who had sexual exposures with persons at risk for HIV infection and had in turn infected their spouses. DE Female Human HIV Infections/*EPIDEMIOLOGY/TRANSMISSION Infant, Newborn Male Pregnancy Pregnancy Complications, Infectious Sex Behavior Singapore/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).