Document 2517 DOCN M94A2517 TI Epidemiological characteristics of HIV/AIDS prevalence in Japan. DT 9412 AU Kodama M; Kodama T; Kodama Res. Inst. Prev. Med., Nagoya, Japan. SO Int Conf AIDS. 1994 Aug 7-12;10(1):286 (abstract no. PC0065). Unique Identifier : AIDSLINE ICA10/94370058 AB OBJECTIVE: The present study investigated the epidemiological characteristics of HIV/AIDS prevalence in Japan so as to clarify the nature of this 20th Century pestilence now spreading in the world. METHODS: We made an access to the problem by attempting a comparison between Japan (a low-risk country) and USA (a high-risk country) by use of both new date and historical data derived from authentic source. RESULTS: Results obtained are as follows: 1) The increasing pattern of HIV/AIDS of Japan is still at the stage of geometric growth (an early stage), whereas that of USA is now approaching its saturation level (an advanced stage), as judged from the chronological transition of AIDS prevalence in the 2 countries. 2) The difference between the 2 countries, as observed with the prevalence of HIV/AIDS in both average citizens and prostitutes, looks so remarkable that one cannot accept causal relationship between HIV infection and AIDS development without assuming the intervention of some discriminating mechanism in the genesis of AIDS. DISCUSSION AND CONCLUSIONS: Our findings are in support of the possibility that the differential risks for AIDS between USA and Japan could be related in its development to the participation of autoimmune mechanism, of which the expression is subject to change depending on the cultural background of a population. DE Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/TRANSMISSION Comparative Study Human HIV Infections/*EPIDEMIOLOGY/TRANSMISSION Japan/EPIDEMIOLOGY Prevalence Risk Factors United States/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).