Document 2533 DOCN M94A2533 TI Sentinel surveillance among pregnant women in northern Togo during 1992 and 1993. DT 9412 AU Mattke P; Grunitzky-Bekele M; Klee E; Deutsche Gesellschaft fur Technische Zusammenarbeit, Germany. SO Int Conf AIDS. 1994 Aug 7-12;10(1):282 (abstract no. PC0051). Unique Identifier : AIDSLINE ICA10/94370042 AB OBJECTIVE: To determine the seroprevalence of HIV-1 and 2 among pregnant women in a rural area of Northern Togo. METHODS: During July/August 1992 and 1993 all women attending antenatal services in the rural area around Dapaong, the largest town in the North of Togo, were tested for HIV-1 and 2 infection by 2nd generation Elisa, confirmed by western blot. Further tests were done for HBsAG by ELISA and Syphilis by TPHA. Socio-economic information was collected according to an standardized questionnaire after informed consent was given. RESULTS: In 1992, 9 women out of 512 (1.8%) were found to be seropositive for HIV-1, of whom 2 (0.4%) showed dual seroreactivity for HIV-1 and 2. 27 (5.8%) women were TPHA positive and 82 (16%) women were positive for HBsAG. Mean age for all women was 24.9 years (range 15-45). Seropositive women tended to be younger than seronegative women (23.0 vs 25.0). Mean parity was 3.4. There was no statistical significant association between positive HIV and Syphilis serology, place of residence and history of travel or blood transfusion. In 1993 15 women out of 497 (3.0%) were found to be seropositive for HIV-1. No case of HIV-2 was detected. 34 (3.0%) women were TPHA positive and 75 (15.1%) HBsAG positive. Mean age was 24.5 years. There was no difference in mean age between seropositive and seronegative women. Again, there was no statistical significant association between HIV and Syphilis serology, place of residence and history of travel or blood transfusion. CONCLUSION: In rural areas in Northern Togo the seroprevalence of HIV-1 among pregnant women is still increasing. The prevalence rate of HIV-2 among this group is low. DE Adolescence Adult Female Human HIV Seropositivity *HIV Seroprevalence HIV-1 HIV-2 Middle Age Population Surveillance Pregnancy Pregnancy Complications, Infectious/*EPIDEMIOLOGY Togo/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).