Document 2547 DOCN M94A2547 TI Female genital herpes--22 years' experience in Tokyo. DT 9412 AU Kawana T; Tokyo University Branch Hospital. SO Int Conf AIDS. 1994 Aug 7-12;10(1):28 (abstract no. 084B). Unique Identifier : AIDSLINE ICA10/94370028 AB OBJECTIVE: The purpose of this study is to study female genital herpes from clinical and virological viewpoint as well as change of this disease during these 22 years. METHODS: More than 500 female genital herpes cases were included, who visited our outpatient clinic between 1971 and 1993. All patients were diagnosed by virus culture. These patients were clinically classified as acute, recurrent and provoked type. The correlation between clinical type and type of herpes simplex virus (HSV) was studied. RESULTS: The number of patients markedly increased around 1980 and has been steady since then. Recently recurrent type has been gradually increasing. In acute (primary) cases, 61% was caused by HSV-1 and remaining 39% by HSV-2. On the other hand, 90% of recurrent type was caused by HSV-2. HSV type distribution changed during this 22 years. In recent years, 45% of primary female genital herpes was caused by HSV-2 where as in 1970s 35% had been caused by HSV-2. DISCUSSION AND CONCLUSIONS: Prevalence of female genital herpes has been increasing during these 22 years. Recently, genital herpes caused by HSV-2 has been increasing, which may result in endemic extension of this disease. DE Female Herpes Genitalis/*EPIDEMIOLOGY/MICROBIOLOGY Herpesvirus 1, Human/ISOLATION & PURIF Herpesvirus 2, Human/ISOLATION & PURIF Human Japan/EPIDEMIOLOGY Virus Cultivation MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).