Document 2572 DOCN M94A2572 TI HIV infection trends in injecting drug users and homo/bisexual men in the area of Madrid (Spain) 1988-1994. DT 9412 AU del Romero J; Garcia S; Rodriguez C; Clavo I; Carrio D; Ballesteros J; C. S. Sandoval.-Comunidad de Madrid. SO Int Conf AIDS. 1994 Aug 7-12;10(1):273 (abstract no. PC0012). Unique Identifier : AIDSLINE ICA10/94370003 AB OBJECTIVE: To ascertain the time trends of HIV infection in population groups with different risk factors in the area of Madrid. POPULATION ANALYSED: We have studied 6.691 subjects (5.804 men and 887 women) with a mean age of 29.6 years (range 17-70), who first attended in a STD/HIV regional clinic between 1.1.88 and 1.1.94, with the aim of ascertaining their HIV serological status. In accordance with HIV infection risk factors, these 6,691 subjects were grouped as follows: 2985 injecting drug users (2.098 males and 887 females) and 3706 homo/bisexual men. METHODS: A HIV serology was performed of all the patients (ELISA 1st-2nd/3rd generation and confirmation by Western-Blot). RESULTS: Overall HIV seroprevalence was 35.0% (2.342/6.691). The annual prevalence of HIV infection in the groups studied is shown in the table below: TABULAR DATA, SEE ABSTRACT VOLUME. We have observed a gradual increase in the demand for the anti-HIV antibody detection test in homo/bisexual men and a contrary trend in injecting drug users. We found the following trends in the annual prevalence of HIV infection: 1.--clearly downward, after 1990, in homo/bisexual men; 2.--Slightly downward, after 1991, in I.D.U.. CONCLUSION: Knowledge of the dissemination of HIV infection, obtained in suitably representative seroepidemiological studies, would allow a preventive health policy with adequate allocation of technical and human resources. DE Adolescence Adult Aged AIDS Serodiagnosis Female Human HIV Infections/*EPIDEMIOLOGY/TRANSMISSION Male Middle Age Risk Factors *Sex Behavior Spain/EPIDEMIOLOGY Substance Abuse, Intravenous/*COMPLICATIONS MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).