Document 2576
 DOCN  M94A2576
 TI    Increasing trend in HIV-1 prevalence among STD heterosexual females:
       data from the National Sentinel Surveillance System. STD Surveillance
       Working Group.
 DT    9412
 AU    Giuliani M; Suligoi B; Centro Operativo AIDS-Istituto Superiore di
       Sanita, Roma, Italy.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):272 (abstract no. PC0008). Unique
       Identifier : AIDSLINE ICA10/94369999
 AB    OBJECTIVES: To monitor HIV-1 seroprevalence in heterosexual patients
       seen in the sentinel STD clinical network in Italy. METHODS: All STD
       patients seen in one of the 47 participating centers, after providing
       informed consent, were tested for anti HIV-1 antibodies. Behavioral and
       clinical data were collected using a standardized data collection form.
       RESULTS: From September 1990 through December 1992, 10,797 heterosexual
       STD patients, no I.V.D.Us., were tested for anti-HIV-1; 3929 (36.4%)
       were females. Two hundred thirty seven patients (2.2%) were HIV-1
       seropositive (150 males, 87 females). Overall HIV-1 seropositivity was
       associated with a history of previous STDs (OR = 2.3: IC95%: 1.7-3.1),
       only in females, with incident herpes genitalis infection (OR = 3.1
       IC95%: 1.6-5.8). Quarterly data demonstrated that the HIV-1
       seroprevalence rose in the total population from 1.4% in September 1990
       to 2.3 in December 1992. Most of the increase was due to an increase in
       seroprevalence among females. In this group, HIV-1 seroprevalence
       increased during the study period from 1.4 to 2.8 (chi-square for trend:
       7.6 p = 0.005). CONCLUSIONS: The data show an increase of HIV-1
       infection among STD female population. The increasing of prevalence of
       HIV-1 infection is consistent with an increase of the proportion of AIDS
       cases reported among females in Italy. The role of herpes genitalis
       infection in the acquisition of HIV-1 in our population, needs to be
       further examined through longitudinal studies.
 DE    Female  Human  *HIV Seroprevalence  *HIV-1  Italy/EPIDEMIOLOGY  Male
       Population Surveillance  Prevalence  Sexually Transmitted
       Diseases/COMPLICATIONS/EPIDEMIOLOGY/  *MICROBIOLOGY  MEETING ABSTRACT

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