Document 2578
 DOCN  M94A2578
 TI    Edinburgh versus Glasgow (1984-93): the difference in HIV prevalence
       among IDUs and the impact on heterosexual spread.
 DT    9412
 AU    Goldberg DJ; Emslie JA; Taylor A; Scott G; Kennedy R; Stewart M;
       Scottish Centre for Infection and Environmental Health, Ruchill;
       Hospital, Glasgow, UK.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):272 (abstract no. PC0006). Unique
       Identifier : AIDSLINE ICA10/94369997
 AB    OBJECTIVES: Ten years on, to assess the impact of the low (< 5%) and
       high (> 30%) prevalence epidemics of HIV among IDUs in two cities 70
       kilometers apart--Edinburgh and Glasgow--on the spread of infection into
       the heterosexual population. METHODS: A variety of surveillance datasets
       including AIDS Registrations, HIV laboratory reports, and unlinked
       anonymous studies of pregnant women, genito-urinary clinic, family
       planning clinic and hospital patient and general practice attenders are
       used to compare and contrast the two epidemics. RESULTS: In Edinburgh
       there is clear evidence of first generation heterosexual spread
       especially from male injectors to their female non-injecting partners;
       second generation spread is occurring but at present the numbers are
       small. In Glasgow first generation spread is minimal and indigenous
       second generation spread almost absent. However, especially in Glasgow,
       imported infection is becoming increasingly prevalent. In both centres
       there is little evidence of HIV entering the heterosexual population via
       infected bisexual men. DISCUSSION: These observations confirm the
       importance of a) sustaining initiatives to prevent HIV among IDUs and b)
       targetting interventions on persons travelling to and from high risk
       areas, in preventing spread of HIV into the wider heterosexual
       community.
 DE    Comparative Study  Female  Human  HIV
       Infections/*EPIDEMIOLOGY/TRANSMISSION  Male  Risk Factors
       Scotland/EPIDEMIOLOGY  *Sex Behavior  Substance Abuse,
       Intravenous/*COMPLICATIONS  MEETING ABSTRACT

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